Hcn4 - hyperpolarization activated cyclic nucleotide-gated potassium channel 4 Gene

Rattus norvegicus

Gene ID: 59266 | Gene type: protein coding

About Hcn4

Summary

Predicted to enable cation channel activity and identical protein binding activity. Involved in cellular response to aldosterone and response to cisplatin. Located in basolateral plasma membrane; neuronal cell body; and terminal bouton. Human ortholog(s) of this gene implicated in Brugada syndrome 8; Gilles de la Tourette syndrome; idiopathic generalized epilepsy; and sick sinus syndrome. Orthologous to human HCN4 (hyperpolarization activated cyclic nucleotide gated Potassium Channel 4). [provided by Alliance of Genome Resources, Apr 2022]

Hcn4 Products(1)

mRNA	Protein	Name
NM_021658.2	NP_067690.1	potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

Protein Preferred Names

Protein Names

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

hyperpolarization-activated, cyclic nucleotide-gated K+ 4

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-18940	Cilobradine		/	Phase 2

Pre-clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13422	Zatebradine hydrochloride	Antagonist	99.87%	Unkown
HY-13422A	Zatebradine	Antagonist	99.27%	Unkown
HY-160505	RO-275	Inhibitor	≥99.0%	Unkown
HY-119102	BPU-11		98.01%	Unkown
HY-RS06049	HCN4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19140	Hcn3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20286	Hcn4 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26794	Hcn4 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hcn4	NCBI	NCBI:10021

Name
Email *

	Sorry, but the email address you supplied was invalid.