Ccnd1 - cyclin D1 Gene

Rattus norvegicus

Gene ID: 58919 | Gene type: protein coding

About Ccnd1

Summary

Enables protein kinase binding activity. Involved in several processes, including animal organ development; response to corticosterone; and response to vitamin E. Located in cytoplasm and nucleus. Used to study prostate Cancer and status epilepticus. Biomarker of impotence; transitional cell carcinoma; and visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); colorectal cancer; hematologic Cancer (multiple); invasive lobular carcinoma; and von Hippel-Lindau disease. Orthologous to human CCND1 (cyclin D1). [provided by Alliance of Genome Resources, Apr 2022]

Ccnd1 Products(1)

mRNA	Protein	Name
NM_171992.5	NP_741989.3	G1/S-specific cyclin-D1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein kinase binding	IPI IPI: Inferred from physical interaction	15809057	RGD
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	8651753	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in Leydig cell differentiation	IMP IMP: Inferred from mutant phenotype	17303663	RGD
involved in animal organ regeneration	IEP IEP: Inferred from expression pattern	16938172	RGD
involved in liver development	IEP IEP: Inferred from expression pattern	15809057	RGD
involved in positive regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	14604889	RGD
involved in response to X-ray	IEP IEP: Inferred from expression pattern	17148264	RGD
involved in response to calcium ion	IEP IEP: Inferred from expression pattern	7980531	RGD
involved in response to corticosterone	IEP IEP: Inferred from expression pattern	12807724	RGD
involved in response to estradiol	IEP IEP: Inferred from expression pattern	17055086	RGD
involved in response to estrogen	IEP IEP: Inferred from expression pattern	17088081	RGD
involved in response to ethanol	IEP IEP: Inferred from expression pattern	17015179	RGD
involved in response to glucocorticoid	IEP IEP: Inferred from expression pattern	16707792	RGD
involved in response to iron ion	IEP IEP: Inferred from expression pattern	16890145	RGD
involved in response to magnesium ion	IEP IEP: Inferred from expression pattern	14566962	RGD
involved in response to organic cyclic compound	IEP IEP: Inferred from expression pattern	17137605	RGD
involved in response to steroid hormone	IEP IEP: Inferred from expression pattern	15975997	RGD
involved in response to vitamin E	IEP IEP: Inferred from expression pattern	17015179	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	12602925	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

G1/S-specific cyclin-D1

Related Agents

Pre-clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N0692	Schisandrol B		99.99%	Unkown
HY-119271	CMLD010509		99.11%	Unkown
HY-168664	CPD-39	Degrader	98.06%	Unkown
HY-168660	CPD-10		/	Unkown
HY-RS02123	CCND1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-119271A	(-)-CMLD010509		/	Unkown
HY-RS16780	Ccnd1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS23220	Ccnd1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ccnd1	NCBI	NCBI:595

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