1. Gene
  2. Apip - APAF1 interacting protein Gene

Apip - APAF1 interacting protein Gene

Mus musculus

Also known as APIP2; CGI-29; Mmrp19

Gene ID: 56369 | Gene type: protein coding

About Apip

Summary

Predicted to enable identical protein binding activity; methylthioribulose 1-phosphate dehydratase activity; and zinc ion binding activity. Involved in regulation of ERK1 and ERK2 cascade. Acts upstream of or within negative regulation of apoptotic process. Predicted to be active in cytoplasm. Orthologous to human APIP (APAF1 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Apip Products(3)

mRNA Protein Name
NM_001355473.1 NP_001342402.1 methylthioribulose-1-phosphate dehydratase isoform 2
NM_001355474.1 NP_001342403.1 methylthioribulose-1-phosphate dehydratase isoform 3
NM_019735.4 NP_062709.3 methylthioribulose-1-phosphate dehydratase isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of apoptotic process IMP
IMP: Inferred from mutant phenotype
15262985 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
15262985 MGI
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
17086211 MGI
involved in regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
17086211 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methylthioribulose-1-phosphate dehydratase

MTRu-1-P dehydratase

monocyte macrophage 19

monocyte/macrophage protein 19

probable methylthioribulose-1-phosphate dehydratase

Orthologs Information

Species Symbol Source ID
Homo sapiens Apip NCBI NCBI:51074