2. Gene
  3. Tlr5 - toll-like receptor 5 Gene

Tlr5 - toll-like receptor 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 53791 | Gene type: protein coding

About Tlr5

Summary

Predicted to enable interleukin-1 receptor binding activity and signaling receptor activity. Predicted to be involved in several processes, including positive regulation of interleukin-8 production; positive regulation of nitric oxide biosynthetic process; and positive regulation of Toll-like Receptor signaling pathway. Predicted to act upstream of or within innate immune response. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. Is expressed in brain; olfactory epithelium; spinal cord; and trunk unsegmented mesenchyme. Human ortholog(s) of this gene implicated in Legionnaires' disease; cystic fibrosis; cystitis; melioidosis; and systemic lupus erythematosus. Orthologous to human TLR5 (toll like receptor 5). [provided by Alliance of Genome Resources, Apr 2022]

Tlr5 Products(1)

mRNA Protein Name
NM_016928.4 NP_058624.3 toll-like receptor 5 precursor
Protein Preferred Names Protein Names

toll-like receptor 5

Tlr5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Tlr5 Q9JLF7 flag Salmonella typhi Q56086
Pull Down
23101627
Cross
Tlr5 Q9JLF7 fliC Salmonella typhimurium A0A0H3NMJ6
Pull Down
23101627
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-116961 TH1020 99.81% Unkown
HY-NP134 Flagellin from S. typhimurium Agonist / Unkown
HY-RS14589 TLR5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16808 Tlr5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23248 Tlr5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991076 Entolimod Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tlr5 NCBI NCBI:7100