Ybx1 - Y box binding protein 1 Gene

Rattus norvegicus

Also known as Yb1; Byb1; Cbfa; Dbpb; Ef1a; Msy1; Nsep1

Gene ID: 500538 | Gene type: protein coding

About Ybx1

Summary

Enables nucleic acid binding activity and p53 binding activity. Involved in several processes, including negative regulation of apoptotic process; negative regulation of Insulin Receptor signaling pathway; and regulation of transcription by RNA polymerase II. Located in several cellular components, including dendrite; neuronal cell body; and perinuclear region of cytoplasm. Part of messenger ribonucleoprotein complex. Biomarker of myocardial infarction. Orthologous to human YBX1 (Y-box binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ybx1 Products(1)

mRNA	Protein	Name
NM_031563.3	NP_113751.3	Y-box-binding protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables RNA binding	IDA IDA: Inferred from direct assay	23159318	RGD
enables mRNA binding	IPI IPI: Inferred from physical interaction	16508950	RGD
enables p53 binding	IMP IMP: Inferred from mutant phenotype	16158057	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	23159318	RGD
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	16278212	RGD
enables single-stranded DNA binding	IDA IDA: Inferred from direct assay	17893273	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of apoptotic process	IDA IDA: Inferred from direct assay	16158057	RGD
involved in negative regulation of insulin receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	12554649	RGD
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	12835324	RGD
involved in positive regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	15615704	RGD
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	15615704	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendrite	IDA IDA: Inferred from direct assay	14559349	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	14559349	RGD
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	16002047	RGD
part of protein-containing complex	IDA IDA: Inferred from direct assay	20596529	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

Y-box-binding protein 1

CBF-A	CCAAT-binding transcription factor 1 subunit A
CCAAT-binding transcription factor I subunit A	DNA binding protein B
EFI-A	Y box transcription factor
YB-1	enhancer factor 1 alpha
enhancer factor 1 subunit A	enhancer factor I subunit A
nucle

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16252	Ybx1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15916	YBX1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS23592	Ybx1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ybx1	NCBI	NCBI:4904
Mus musculus	Ybx1	NCBI	NCBI:22608

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