Izumo1 - izumo sperm-oocyte fusion 1 Gene

Rattus norvegicus

Gene ID: 499152 | Gene type: protein coding

About Izumo1

Summary

Enables protein homodimerization activity. Predicted to be involved in fusion of sperm to egg plasma membrane involved in single fertilization; heterotypic cell-cell adhesion; and sperm-egg recognition. Predicted to be located in acrosomal vesicle. Predicted to be active in acrosomal membrane and plasma membrane. Predicted to be integral component of membrane. Orthologous to human IZUMO1 (izumo sperm-egg fusion 1). [provided by Alliance of Genome Resources, Apr 2022]

Izumo1 Products(1)

mRNA	Protein	Name
NM_001017514.1	NP_001017514.1	izumo sperm-egg fusion protein 1 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	19658160	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

izumo sperm-egg fusion protein 1

OBF	izumo sperm-egg fusion 1
oocyte binding/fusion factor	sperm-specific protein izumo

Related Agents

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07004	IZUMO1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS07005	IZUMO1R Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19263	Izumo1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21242	Izumo1r Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25752	Izumo1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27759	Izumo1r Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Izumo1	NCBI	NCBI:284359
Mus musculus	Izumo1	NCBI	NCBI:73456

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