2. Gene
  3. Mafa - MAF bZIP transcription factor A Gene

Mafa - MAF bZIP transcription factor A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1562627

Gene ID: 366949 | Gene type: protein coding

About Mafa

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including Insulin secretion; nitric oxide mediated signal transduction; and response to glucose. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Biomarker of diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAFA (MAF bZIP transcription factor A). [provided by Alliance of Genome Resources, Apr 2022]

Mafa Products(1)

mRNA Protein Name
NM_001399773.1 NP_001386702.1 transcription factor MafA
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18042454 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor MafA

pancreatic beta-cell-specific transcriptional activator

v-maf avian musculoaponeurotic fibrosarcoma oncogene A

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A

v-maf muscul

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07958 MAFA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19615 Mafa Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26110 Mafa Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mafa NCBI NCBI:389692
Mus musculus Mafa NCBI NCBI:378435