2. Gene
  3. Mafa - v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) Gene

Mafa - v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as RIPE3b1

Gene ID: 378435 | Gene type: protein coding

About Mafa

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including lens vesicle; myotome; nervous system; pancreas; and spleen. Used to study maturity-onset diabetes of the young and type 2 diabetes mellitus. Orthologous to human MAFA (MAF bZIP transcription factor A). [provided by Alliance of Genome Resources, Apr 2022]

Mafa Products(1)

mRNA Protein Name
NM_194350.2 NP_919331.1 transcription factor MafA
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
12368292 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12368292 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12368292 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12368292 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12917329 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12368292 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
12368292 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor MafA

Mafa homolog

V-maf musculoaponeurotic fibrosarcoma oncogene homolog A

pancreatic beta-cell-specific transcriptional activator

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07958 MAFA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19615 Mafa Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26110 Mafa Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mafa NCBI NCBI:389692