2. Gene
  3. Osbp - oxysterol binding protein Gene

Osbp - oxysterol binding protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 365410 | Gene type: protein coding

About Osbp

Summary

Predicted to enable several functions, including phosphatidylinositol-4-phosphate binding activity; sterol binding activity; and sterol transfer activity. Involved in positive regulation of Insulin secretion involved in cellular response to glucose stimulus; positive regulation of secretory granule organization; and positive regulation of tyrosine phosphorylation of STAT protein. Located in cytosol. Orthologous to human OSBP (oxysterol binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Osbp Products(1)

mRNA Protein Name
NM_001108927.2 NP_001102397.1 oxysterol-binding protein 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
29540530 RGD
involved in positive regulation of protein modification process IMP
IMP: Inferred from mutant phenotype
18230613 RGD
involved in positive regulation of secretory granule organization IMP
IMP: Inferred from mutant phenotype
29540530 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oxysterol-binding protein 1

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17514 Itraconazole 99.59% Yes
Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101213 OSW-1 Antagonist 99.66% Unkown
HY-124806 TTP-8307 Inhibitor 99.90% Unkown
HY-17514S2 Itraconazole-d9 97.86% Unkown
HY-148391 23-Oxa-OSW-1 Inhibitor / Unkown
HY-156275 OSBP-IN-1 / Unkown
HY-RS09835 OSBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09836 OSBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-163891 Antifungal agent 107 Inhibitor / Unkown
HY-RS19928 Osbp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26430 Osbp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Osbp NCBI NCBI:5007