2. Gene
  3. HCFC1 - Hcfc1 host cell factor C1 Gene

HCFC1 - Hcfc1 host cell factor C1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as HCF; HCF-1; RGD1563804

Gene ID: 363519 | Gene type: protein coding

About HCFC1

Summary

Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and transcription coactivator activity. Involved in cellular response to organic cyclic compound and negative regulation of transcription by RNA polymerase II. Located in several cellular components, including axon; dendrite; and nucleus. Human ortholog(s) of this gene implicated in methylmalonic acidemia and homocysteinemia cblX type. Orthologous to human HCFC1 (host cell factor C1). [provided by Alliance of Genome Resources, Apr 2022]

HCFC1 Products(2)

mRNA Protein Name
NM_001414734.1 NP_001401663.1 host cell factor 1
NM_001139507.2 NP_001132979.1 host cell factor 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to organic cyclic compound IEP
IEP: Inferred from expression pattern
22383875 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21909281 RGD
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
24250814 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
24250814 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
22383875 RGD
located in dendrite IDA
IDA: Inferred from direct assay
22383875 RGD
located in nuclear chromosome IDA
IDA: Inferred from direct assay
24250814 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

host cell factor 1

C1 factor

host cell factor 1-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06042 HCFC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19688 Hcfc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26182 Hcfc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HCFC1 NCBI NCBI:3054