2. Gene
  3. Uchl5 - ubiquitin C-terminal hydrolase L5 Gene

Uchl5 - ubiquitin C-terminal hydrolase L5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 360853 | Gene type: protein coding

About Uchl5

Summary

Predicted to enable endopeptidase inhibitor activity; Proteasome binding activity; and thiol-dependent Deubiquitinase. Predicted to be involved in several processes, including brain development; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; and positive regulation of smoothened signaling pathway. Part of cytosolic Proteasome complex. Orthologous to human UCHL5 (ubiquitin C-terminal hydrolase L5). [provided by Alliance of Genome Resources, Apr 2022]

Uchl5 Products(3)

mRNA Protein Name
NM_001393849.1 NP_001380778.1 ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform 1
NM_001393850.1 NP_001380779.1 ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform 2
NM_001393851.1 NP_001380780.1 ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform 3
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
part of cytosolic proteasome complex IDA
IDA: Inferred from direct assay
19609968 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase isozyme L5

ubiquitin carboxyl-terminal esterase L5

ubiquitin carboxyl-terminal hydrolase L5

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13989 b-AP15 98.57% Unkown
HY-149230 USP28-IN-4 Inhibitor 99.35% Unkown
HY-149229 USP28-IN-3 Inhibitor 98.26% Unkown
HY-149228 USP28-IN-2 Inhibitor / Unkown
HY-164689 Cadmium pyrithione Inhibitor / Unkown
HY-RS15402 UCHL5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-15432 (E/Z)-NSC-687852 / Unkown
HY-RS18192 Uchl5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24666 Uchl5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uchl5 NCBI NCBI:51377