2. Gene
  3. Tdp1 - tyrosyl-DNA phosphodiesterase 1 Gene

Tdp1 - tyrosyl-DNA phosphodiesterase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 314380 | Gene type: protein coding

About Tdp1

Summary

Predicted to enable 3'-tyrosyl-DNA phosphodiesterase activity; double-stranded DNA binding activity; and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair and single strand break repair. Predicted to act upstream of or within DNA repair. Predicted to be located in cytoplasm; nucleoplasm; and plasma membrane. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 1 with axonal neuropathy. Orthologous to human TDP1 (tyrosyl-DNA phosphodiesterase 1). [provided by Alliance of Genome Resources, Apr 2022]

Tdp1 Products(1)

mRNA Protein Name
NM_001031657.1 NP_001026827.1 tyrosyl-DNA phosphodiesterase 1
Protein Preferred Names Protein Names

tyrosyl-DNA phosphodiesterase 1

tyr-DNA phosphodiesterase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-110137 Furamidine dihydrochloride Inhibitor ≥99.0% Unkown
HY-119372 TDP1 Inhibitor-1 Inhibitor 98.33% Unkown
HY-W177546 CD00509 Inhibitor ≥98.0% Unkown
HY-147750 TDP1 Inhibitor-2 Inhibitor 99.84% Unkown
HY-157886 TDP1 Inhibitor-3 Inhibitor 98.10% Unkown
HY-161853 TX-2552 Inhibitor 99.69% Unkown
HY-110137A Furamidine Inhibitor / Unkown
HY-176409 Phosphodiesterase-IN-4 Inhibitor / Unkown
HY-RS14332 TDP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17650 Tdp1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24110 Tdp1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tdp1 NCBI NCBI:55775
Mus musculus Tdp1 NCBI NCBI:104884