2. Gene
  3. Pappa - pappalysin Gene

Pappa - pappalysin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pappa1

Gene ID: 313262 | Gene type: protein coding

About Pappa

Summary

Predicted to enable metalloendopeptidase activity. Involved in several processes, including female pregnancy; response to follicle-stimulating hormone; and response to glucocorticoid. Located in extracellular space. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human PAPPA (pappalysin 1). [provided by Alliance of Genome Resources, Apr 2022]

Pappa Products(1)

mRNA Protein Name
NM_001401319.1 NP_001388248.1 pappalysin-1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in female pregnancy IEP
IEP: Inferred from expression pattern
2423447 RGD
involved in protein catabolic process IMP
IMP: Inferred from mutant phenotype
15754336 RGD
involved in response to dexamethasone IMP
IMP: Inferred from mutant phenotype
15754336 RGD
involved in response to follicle-stimulating hormone IEP
IEP: Inferred from expression pattern
15087430 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
15754336 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pappalysin-1

pappalysin 1

pregnancy-associated plasma protein A

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10028 PAPPA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10029 PAPPA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17709 Pappa Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24174 Pappa Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pappa NCBI NCBI:5069