2. Gene
  3. Ufl1 - Ufm1-specific ligase 1 Gene

Ufl1 - Ufm1-specific ligase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Maxer; RGD1309308

Gene ID: 313115 | Gene type: protein coding

About Ufl1

Summary

Predicted to enable UFM1 Ligase activity and protein kinase binding activity. Involved in negative regulation of apoptotic process. Predicted to be located in several cellular components, including endoplasmic reticulum; neuron projection; and site of double-strand break. Predicted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human UFL1 (UFM1 specific Ligase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ufl1 Products(1)

mRNA Protein Name
NM_001126279.1 NP_001119751.1 E3 UFM1-protein ligase 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
21494687 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 UFM1-protein ligase 1

E3 UFM1-protein transferase 1

multiple alpha-helix protein located at ER

regulator of C53/LZAP and DDRGK1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15415 UFL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19395 Ufl1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25887 Ufl1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ufl1 NCBI NCBI:23376