2. Gene
  3. Ano1 - anoctamin 1 Gene

Ano1 - anoctamin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Tmem16a

Gene ID: 309135 | Gene type: protein coding

About Ano1

Summary

Enables intracellular calcium activated Chloride Channel activity; iodide transmembrane transporter activity; and signaling receptor binding activity. Involved in cellular response to peptide; chloride transmembrane transport; and iodide transport. Located in membrane raft and plasma membrane. Orthologous to human ANO1 (anoctamin 1). [provided by Alliance of Genome Resources, Apr 2022]

Ano1 Products(1)

mRNA Protein Name
NM_001107564.1 NP_001101034.1 anoctamin-1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables intracellularly calcium-gated chloride channel activity IDA
IDA: Inferred from direct assay
24081981 RGD
enables intracellularly calcium-gated chloride channel activity IMP
IMP: Inferred from mutant phenotype
20421283 RGD
enables iodide transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
25201006 RGD
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
23982204 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to peptide IMP
IMP: Inferred from mutant phenotype
20335661 RGD
involved in chloride transmembrane transport IMP
IMP: Inferred from mutant phenotype
23982204 RGD
involved in chloride transport IMP
IMP: Inferred from mutant phenotype
25201006 RGD
involved in iodide transport IMP
IMP: Inferred from mutant phenotype
25201006 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

anoctamin-1

anoctamin 1, calcium activated chloride channel

transmembrane protein 16A

Related Agents

Pre-clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100612 T16Ainh-A01 Inhibitor ≥99.0% Unkown
HY-119981 Ani9 Inhibitor 99.12% Unkown
HY-146334 DFBTA Inhibitor 99.25% Unkown
HY-146320 ANO1-IN-1 Inhibitor 99.57% Unkown
HY-105917 Emidurdar Inhibitor 99.41% Yes
HY-118170 T16A(inh)-C01 Inhibitor 90% Unkown
HY-N5101 Kobusin 99.93% Unkown
HY-146321 ANO1-IN-2 Inhibitor / Unkown
HY-147874 ANO1-IN-3 / Unkown
HY-153508 ANO1-IN-4 Inhibitor / Unkown
HY-RS00740 ANO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00750 ANOS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17326 Ano1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23781 Ano1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990337 Anti-ANO1/TMEM16A Antibody Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ano1 NCBI NCBI:55107