2. Gene
  3. Dsp - desmoplakin Gene

Dsp - desmoplakin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 306871 | Gene type: protein coding

About Dsp

Summary

Predicted to enable protein kinase C binding activity; scaffold protein binding activity; and structural molecule activity. Involved in wound healing. Located in desmosome and fascia adherens. Human ortholog(s) of this gene implicated in Carvajal syndrome; arrhythmogenic right ventricular cardiomyopathy; arrhythmogenic right ventricular dysplasia 8; and dilated cardiomyopathy. Orthologous to human DSP (desmoplakin). [provided by Alliance of Genome Resources, Apr 2022]

Dsp Products(2)

mRNA Protein Name
XM_017600713.2 XP_017456202.1 desmoplakin isoform X2
XM_225259.10 XP_225259.4 desmoplakin isoform X1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
NOT located in adherens junction IDA
IDA: Inferred from direct assay
2463257 RGD
located in desmosome IDA
IDA: Inferred from direct assay
16406610 RGD
located in fascia adherens IDA
IDA: Inferred from direct assay
16406610 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

desmoplakin

Related Agents

Clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Phase
HY-17638 Mizagliflozin Inhibitor 99.20% Phase 2
HY-139575A Guretolimod hydrochloride 98.67% Phase 2
HY-139575 Guretolimod Agonist / Phase 2
HY-125079 DSP-2230 Inhibitor 98.33% Phase 1
HY-111419 DSP-1053 99.75% Phase 1
HY-111419A DSP-1053 benzenesulfonate / Phase 1
HY-114300 DSP-0565 Agonist / Phase 1
Pre-clinical Phase
Bioactive Molecules (18)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-118759 DSP Crosslinker 99.80% Unkown
HY-108652 α,β-Methylene-ATP trisodium Agonist 99.75% Unkown
HY-103210 DSP-4 hydrochloride ≥98.0% Unkown
HY-156794 Enzomenib Inhibitor 99.88% Unkown
HY-121602 DSP 4 free base / Unkown
HY-134440 α,β-Methylene-ATP dilithium Agonist / Unkown
HY-134440A α,β-Methylene-ATP Agonist / Unkown
HY-163728 DSP-6745 Modulator / Unkown
HY-17638A Mizagliflozin (sebacate) Inhibitor / Unkown
HY-RS04026 DSP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04027 DSPP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-118759S DSP Crosslinker-d8 / Unkown
HY-168631 Antibacterial agent 254 Inhibitor / Unkown
HY-177058 DSP30 Agonist / Unkown
HY-RS17087 Dsp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21329 Dspp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23531 Dsp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27848 Dspp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dsp NCBI NCBI:1832