2. Gene
  3. Tfap2a - transcription factor AP-2 alpha Gene

Tfap2a - transcription factor AP-2 alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Tcfap2a

Gene ID: 306862 | Gene type: protein coding

About Tfap2a

Summary

Enables sequence-specific DNA binding activity. Involved in several processes, including Schwann cell development; response to lipopolysaccharide; and response to water deprivation. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in branchiooculofacial syndrome. Orthologous to human TFAP2A (transcription factor AP-2 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Tfap2a Products(1)

mRNA Protein Name
NM_001107345.2 NP_001100815.1 transcription factor AP-2-alpha
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17762867 RGD
Biological Process GO Annotation Evidence Reference Source
involved in Schwann cell development IEP
IEP: Inferred from expression pattern
11553286 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21039521 RGD
involved in response to lipopolysaccharide IDA
IDA: Inferred from direct assay
11688998 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor AP-2-alpha

AP-2 transcription factor

AP2-alpha

activating enhancer-binding protein 2-alpha

activator protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14408 TFAP2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19271 Tfap2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25760 Tfap2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tfap2a NCBI NCBI:7020