2. Gene
  3. Tpr - translocated promoter region, nuclear basket protein Gene

Tpr - translocated promoter region, nuclear basket protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 304862 | Gene type: protein coding

About Tpr

Summary

Predicted to enable several functions, including dynein complex binding activity; mitogen-activated protein kinase binding activity; and protein homodimerization activity. Predicted to be a structural constituent of nuclear pore. Involved in positive regulation of protein export from nucleus and protein export from nucleus. Located in nuclear inclusion body; nuclear membrane; and nuclear periphery. Part of nuclear pore nuclear basket. Orthologous to human TPR (translocated promoter region, nuclear basket protein). [provided by Alliance of Genome Resources, Apr 2022]

Tpr Products(1)

mRNA Protein Name
NM_001107185.1 NP_001100655.2 nucleoprotein TPR
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
NOT involved in nuclear pore complex assembly IMP
IMP: Inferred from mutant phenotype
11839768 RGD
involved in positive regulation of protein export from nucleus IMP
IMP: Inferred from mutant phenotype
11839768 RGD
involved in protein export from nucleus IMP
IMP: Inferred from mutant phenotype
11839768 RGD
NOT involved in regulation of protein import into nucleus IMP
IMP: Inferred from mutant phenotype
11839768 RGD
Cellular Component GO Annotation Evidence Reference Source
located in nuclear inclusion body IDA
IDA: Inferred from direct assay
11839768 RGD
located in nuclear membrane IDA
IDA: Inferred from direct assay
11839768 RGD
located in nuclear periphery IDA
IDA: Inferred from direct assay
11839768 RGD
part of nuclear pore nuclear basket IDA
IDA: Inferred from direct assay
11839768 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleoprotein TPR

NPC-associated intranuclear protein

megator

translocated promoter region (to activated MET oncogene)

translocated promoter region protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103241 Ro 90-7501 99.10% Unkown
HY-125759 3-Phenyltoxoflavin Inhibitor 99.76% Unkown
HY-P1896 Hsp70-derived octapeptide 98.01% Unkown
HY-P11185 Hsp90β decapeptide / Unkown
HY-RS14946 TPR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18457 Tpr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24938 Tpr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tpr NCBI NCBI:7175
Mus musculus Tpr NCBI NCBI:108989