2. Gene
  3. Bbs4 - Bardet-Biedl syndrome 4 Gene

Bbs4 - Bardet-Biedl syndrome 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 300754 | Gene type: protein coding

About Bbs4

Summary

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; cytoskeletal protein binding activity; and protein-macromolecule adaptor activity. Involved in protein localization to centrosome. Predicted to be located in several cellular components, including ciliary membrane; microtubule organizing center; and photoreceptor cell cilium. Predicted to be part of BBSome. Predicted to be active in ciliary basal body. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 4; morbid obesity; and obesity. Orthologous to human BBS4 (Bardet-Biedl syndrome 4). [provided by Alliance of Genome Resources, Apr 2022]

Bbs4 Products(1)

mRNA Protein Name
NM_001106826.1 NP_001100296.1 Bardet-Biedl syndrome 4 protein
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in protein localization to centrosome IGI
IGI: Inferred from genetic interaction
18762586 RGD
involved in protein localization to centrosome IMP
IMP: Inferred from mutant phenotype
18762586 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Bardet-Biedl syndrome 4 protein

Bardet-Biedl syndrome 4 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12124 BBS-4 Inhibitor 99.51% Unkown
HY-RS01388 BBS4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17738 Bbs4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24203 Bbs4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bbs4 NCBI NCBI:585