2. Gene
  3. Rbx1 - ring-box 1 Gene

Rbx1 - ring-box 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 300084 | Gene type: protein coding

About Rbx1

Summary

Predicted to enable cullin family protein binding activity; ubiquitin protein Ligase binding activity; and ubiquitin-like protein Ligase activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cellular protein metabolic process; and protein modification by small protein conjugation. Predicted to act upstream of or within protein K48-linked ubiquitination; protein catabolic process; and protein monoubiquitination. Part of VCB complex. Orthologous to human RBX1 (ring-box 1). [provided by Alliance of Genome Resources, Apr 2022]

Rbx1 Products(1)

mRNA Protein Name
NM_001034135.2 NP_001029307.1 E3 ubiquitin-protein ligase RBX1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
10213691 RGD
Cellular Component GO Annotation Evidence Reference Source
part of VCB complex IDA
IDA: Inferred from direct assay
10213691 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RBX1

RING-box protein 1

ring-box 1, E3 ubiquitin protein ligase

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14658 Thalidomide Inducer 99.98% Yes
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14658S Thalidomide-d4 Inducer 98.00% Unkown
HY-RS11776 RBX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18150 Rbx1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24625 Rbx1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbx1 NCBI NCBI:9978