Nmnat1 - nicotinamide nucleotide adenylyltransferase 1 Gene

Rattus norvegicus

Gene ID: 298653 | Gene type: protein coding

About Nmnat1

Summary

Predicted to enable identical protein binding activity; nicotinamide-nucleotide adenylyltransferase activity; and nicotinate-nucleotide adenylyltransferase activity. Involved in negative regulation of apoptotic DNA fragmentation; negative regulation of neuron apoptotic process; and positive regulation of MAPK cascade. Located in cytoplasm and nucleus. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9 and spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis. Orthologous to human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nmnat1 Products(1)

mRNA	Protein	Name
NM_001037556.2	NP_001032645.2	nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

Protein Preferred Names

Protein Names

nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

nicotinamide mononucleotide adenylyl transferase 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-W615108B	β-Nicotinamide mononucleotide, reduced form disodium		99.55%	Unkown
HY-161712	Nampt-IN-12	Inhibitor	99.76%	Unkown
HY-RS09382	NMNAT1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS18008	Nmnat1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS24481	Nmnat1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nmnat1	NCBI	NCBI:64802

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