2. Gene
  3. Tpk1 - thiamine pyrophosphokinase Gene

Tpk1 - thiamine pyrophosphokinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 29807 | Gene type: protein coding

About Tpk1

Summary

Enables thiamine diphosphokinase activity. Acts upstream of or within thiamine metabolic process. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Human ortholog(s) of this gene implicated in inherited metabolic disorder. Orthologous to human TPK1 (thiamin pyrophosphokinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Tpk1 Products(2)

mRNA Protein Name
NM_001311111.1 NP_001298040.1 thiamin pyrophosphokinase 1 isoform 2
NM_013861.4 NP_038889.1 thiamin pyrophosphokinase 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables thiamine diphosphokinase activity IDA
IDA: Inferred from direct assay
10567383 MGI
enables thiamine diphosphokinase activity IMP
IMP: Inferred from mutant phenotype
38547260 MGI
Biological Process GO Annotation Evidence Reference Source
involved in thiamine diphosphate biosynthetic process IDA
IDA: Inferred from direct assay
10567383 MGI
involved in thiamine diphosphate biosynthetic process IMP
IMP: Inferred from mutant phenotype
38547260 MGI
acts upstream of or within thiamine metabolic process IDA
IDA: Inferred from direct assay
10567383 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cytosol IDA
IDA: Inferred from direct assay
8182042 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thiamin pyrophosphokinase 1

mTPK1

thiamine pyrophosphokinase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14935 TPK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18640 Tpk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25125 Tpk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tpk1 NCBI NCBI:27010