HELLS - Hells helicase, lymphoid specific Gene

About HELLS

Summary

Predicted to enable chromatin binding activity. Predicted to be involved in DNA metabolic process; heterochromatin organization; and lymphocyte proliferation. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; heterochromatin assembly; and negative regulation of intrinsic apoptotic signaling pathway. Predicted to be located in chromosome, centromeric region. Predicted to be active in nucleus and pericentric heterochromatin. Human ortholog(s) of this gene implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 4. Orthologous to human HELLS (helicase, lymphoid specific). [provided by Alliance of Genome Resources, Apr 2022]