2. Gene
  3. Ptpmt1 - protein tyrosine phosphatase, mitochondrial 1 Gene

Ptpmt1 - protein tyrosine phosphatase, mitochondrial 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Plip

Gene ID: 29390 | Gene type: protein coding

About Ptpmt1

Summary

Predicted to enable phosphatidylglycerophosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Involved in negative regulation of Insulin secretion involved in cellular response to glucose stimulus. Is integral component of mitochondrial inner membrane. Orthologous to human PTPMT1 (protein tyrosine Phosphatase mitochondrial 1). [provided by Alliance of Genome Resources, Apr 2022]

Ptpmt1 Products(1)

mRNA Protein Name
NM_001105726.1 NP_001099196.1 phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
20167843 RGD
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
18385140 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

PTEN-like phosphatase

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108547 Alexidine dihydrochloride 99.68% Unkown
HY-B1474 Alexidine Inhibitor / Unkown
HY-RS11414 PTPMT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18311 Ptpmt1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24789 Ptpmt1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptpmt1 NCBI NCBI:114971