Fgf7 - fibroblast growth factor 7 Gene

Rattus norvegicus

Also known as Kgf; Fgf5b; KGF/FGF7

Gene ID: 29348 | Gene type: protein coding

About Fgf7

Summary

Enables growth factor activity; heparin binding activity; and type 2 Fibroblast Growth Factor receptor binding activity. Involved in several processes, including ovarian follicle development; phosphatidylcholine biosynthetic process; and surfactant homeostasis. Located in extracellular space. Orthologous to human FGF7 (Fibroblast Growth Factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Fgf7 Products(1)

mRNA	Protein	Name
NM_022182.1	NP_071518.1	fibroblast growth factor 7 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables growth factor activity	IMP IMP: Inferred from mutant phenotype	11597120	RGD
enables heparin binding	IDA IDA: Inferred from direct assay	9843417	RGD
enables type 2 fibroblast growth factor receptor binding	IDA IDA: Inferred from direct assay	9843417	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in lung development	IMP IMP: Inferred from mutant phenotype	11316745	RGD
involved in ovarian follicle development	IMP IMP: Inferred from mutant phenotype	16000551	RGD
involved in phosphatidylcholine biosynthetic process	IMP IMP: Inferred from mutant phenotype	11316745	RGD
involved in phospholipid biosynthetic process	IMP IMP: Inferred from mutant phenotype	11316745	RGD
involved in positive regulation of epithelial cell proliferation	IDA IDA: Inferred from direct assay	1491693	RGD
involved in positive regulation of epithelial cell proliferation	IMP IMP: Inferred from mutant phenotype	11597120	RGD
involved in surfactant homeostasis	IMP IMP: Inferred from mutant phenotype	11316745	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in extracellular space	IDA IDA: Inferred from direct assay	11597120	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

fibroblast growth factor 7

FGF-7	HBGF-7
Keratinocyte Growth Factor Fgf-7	fibroblast growth factor 5b
heparin-binding growth factor 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04905	FGF7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS16714	Fgf7 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS23149	Fgf7 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Fgf7	NCBI	NCBI:2252

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