2. Gene
  3. Fbl - fibrillarin Gene

Fbl - fibrillarin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 292747 | Gene type: protein coding

About Fbl

Summary

Predicted to enable several functions, including ATPase binding activity; S-adenosylmethionine-dependent methyltransferase activity; and TFIID-class transcription factor complex binding activity. Predicted to be involved in histone glutamine methylation; ncRNA processing; and snoRNA localization. Predicted to act upstream of or within sno(s)RNA metabolic process. Located in Cajal body; chromosome; and dense fibrillar component. Orthologous to human FBL (fibrillarin). [provided by Alliance of Genome Resources, Apr 2022]

Fbl Products(1)

mRNA Protein Name
NM_001025643.1 NP_001020814.1 rRNA 2'-O-methyltransferase fibrillarin
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12446766 RGD
Cellular Component GO Annotation Evidence Reference Source
located in Cajal body IDA
IDA: Inferred from direct assay
11135260 RGD
located in chromosome IDA
IDA: Inferred from direct assay
2752212 RGD
located in dense fibrillar component IDA
IDA: Inferred from direct assay
2414294 RGD
located in nucleoplasm IDA
IDA: Inferred from direct assay
2752212 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rRNA 2'-O-methyltransferase fibrillarin

U6 snRNA 2'-O-methyltransferase fibrillarin

histone-glutamine methyltransferase

nucleolar protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04769 FBL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18734 Fbl Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25221 Fbl Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbl NCBI NCBI:2091
Mus musculus Fbl NCBI NCBI:14113