2. Gene
  3. Fbl - fibrillarin Gene

Fbl - fibrillarin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as FIB; FLRN; RNU3IP1

Gene ID: 14113 | Gene type: protein coding

About Fbl

Summary

Enables RNA binding activity. Acts upstream of or within sno(s)RNA metabolic process. Located in Cajal body and granular component. Is expressed in several structures, including central nervous system; early conceptus; neural retina; oocyte; and submandibular gland primordium. Orthologous to human FBL (fibrillarin). [provided by Alliance of Genome Resources, Apr 2022]

Fbl Products(2)

mRNA Protein Name
NM_001412420.1 NP_001399349.1 rRNA 2'-O-methyltransferase fibrillarin isoform 2
NM_007991.4 NP_032017.2 rRNA 2'-O-methyltransferase fibrillarin isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables RNA binding IPI
IPI: Inferred from physical interaction
24174535 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within sno(s)RNA metabolic process IMP
IMP: Inferred from mutant phenotype
14612397 MGI
Cellular Component GO Annotation Evidence Reference Source
located in Cajal body IDA
IDA: Inferred from direct assay
7768196 MGI
located in granular component IDA
IDA: Inferred from direct assay
15485902 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
7772340 MGI
located in nucleus IDA
IDA: Inferred from direct assay
32017896 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rRNA 2'-O-methyltransferase fibrillarin

U6 snRNA 2'-O-methyltransferase fibrillarin

histone-glutamine methyltransferase

nucleolar protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04769 FBL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18734 Fbl Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25221 Fbl Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbl NCBI NCBI:2091