2. Gene
  3. Hpn - hepsin Gene

Hpn - hepsin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 29135 | Gene type: protein coding

About Hpn

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in several processes, including cochlea morphogenesis; positive regulation of nitrogen compound metabolic process; and regulation of epithelial cell proliferation. Predicted to act upstream of or within several processes, including Cholesterol homeostasis; negative regulation of Alkaline Phosphatase activity; and sensory perception of sound. Predicted to be located in several cellular components, including cell surface; endoplasmic reticulum membrane; and neuronal cell body. Predicted to be integral component of plasma membrane. Predicted to colocalize with nuclear membrane. Orthologous to human HPN (hepsin). [provided by Alliance of Genome Resources, Apr 2022]

Hpn Products(1)

mRNA Protein Name
NM_017112.1 NP_058808.1 serine protease hepsin precursor
Protein Preferred Names Protein Names

serine protease hepsin

hepsin (transmembrane protease, serine 1)

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B2087 Glycerol phenylbutyrate 99.81% Yes
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-135366 HPN-01 Inhibitor 98.61% Phase 1
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P990920 Gocatamig Inhibitor ≥99.0% Phase 2
HY-P991088 HPN536 Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06342 HPN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18736 Hpn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25223 Hpn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hpn NCBI NCBI:3249
Mus musculus Hpn NCBI NCBI:15451