2. Gene
  3. Eif4g1 - eukaryotic translation initiation factor 4 gamma 1 Gene

Eif4g1 - eukaryotic translation initiation factor 4 gamma 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 287986 | Gene type: protein coding

About Eif4g1

Summary

Enables eukaryotic initiation factor 4E binding activity. Involved in lung development and response to ethanol. Part of eukaryotic translation initiation factor 4F complex. Is active in postsynapse. Human ortholog(s) of this gene implicated in late onset Parkinson's disease. Orthologous to human EIF4G1 (eukaryotic translation initiation factor 4 gamma 1). [provided by Alliance of Genome Resources, Apr 2022]

Eif4g1 Products(8)

mRNA Protein Name
XM_008768835.3 XP_008767057.1 eukaryotic translation initiation factor 4 gamma 1 isoform X5
XM_006248584.4 XP_006248646.1 eukaryotic translation initiation factor 4 gamma 1 isoform X4
XM_017598184.2 XP_017453673.1 eukaryotic translation initiation factor 4 gamma 1 isoform X2
XM_006248583.3 XP_006248645.1 eukaryotic translation initiation factor 4 gamma 1 isoform X3
XM_017598182.2 XP_017453671.1 eukaryotic translation initiation factor 4 gamma 1 isoform X1
XM_006248585.4 XP_006248647.1 eukaryotic translation initiation factor 4 gamma 1 isoform X4
XM_006248581.4 XP_006248643.1 eukaryotic translation initiation factor 4 gamma 1 isoform X1
XM_017598183.1 XP_017453672.1 eukaryotic translation initiation factor 4 gamma 1 isoform X1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables eukaryotic initiation factor 4E binding IPI
IPI: Inferred from physical interaction
18952566 RGD
Biological Process GO Annotation Evidence Reference Source
involved in lung development IEP
IEP: Inferred from expression pattern
15388509 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
15388509 RGD
Cellular Component GO Annotation Evidence Reference Source
part of eukaryotic translation initiation factor 4F complex IDA
IDA: Inferred from direct assay
18952566 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
12451124 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 4 gamma 1

eukaryotic translation initiation factor 4 gamma 1-like

voltage-dependent P/Q-type calcium channel subunit alpha-1A-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-19560 SBI-0640756 Inhibitor 99.75% Unkown
HY-RS04281 EIF4G1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-164524 SBI-0640726 Inhibitor / Unkown
HY-RS19254 Eif4g1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25743 Eif4g1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif4g1 NCBI NCBI:1981