2. Gene
  3. Trap1 - TNF receptor-associated protein 1 Gene

Trap1 - TNF receptor-associated protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 287069 | Gene type: protein coding

About Trap1

Summary

Enables protein kinase binding activity. Involved in negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide. Located in mitochondrial inner membrane and mitochondrial intermembrane space. Orthologous to human TRAP1 (TNF Receptor associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Trap1 Products(1)

mRNA Protein Name
NM_001039001.1 NP_001034090.1 heat shock protein 75 kDa, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17579517 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
17579517 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide IMP
IMP: Inferred from mutant phenotype
17579517 RGD
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
17579517 RGD
located in mitochondrial intermembrane space IDA
IDA: Inferred from direct assay
17579517 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heat shock protein 75 kDa, mitochondrial

HSP 75

TNFR-associated protein 1

TRAP-1

tumor necrosis factor type 1 receptor-associated protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (18)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W111141 BCN-OH 99.15% Unkown
HY-10214 SNX-2112 99.49% Unkown
HY-10942 VER-82576 Inhibitor 98.76% Unkown
HY-147696 SMTIN-T140 99.58% Unkown
HY-W004292 1-Undecanol 99.79% Unkown
HY-117395 PU-H54 Inhibitor 99.04% Unkown
HY-115781 DN401 Inhibitor ≥99.0% Unkown
HY-155063 TRAP1-IN-1 Inhibitor 96.03% Unkown
HY-169369 TRAP-1 99.69% Unkown
HY-144830 6BrCaQ Inhibitor / Unkown
HY-144831 6BrCaQ-C10-TPP Inhibitor / Unkown
HY-155064 TRAP1-IN-2 Inhibitor / Unkown
HY-RS14454 TGFBRAP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14984 TRAP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W004292S 1-Undecanol-d23 / Unkown
HY-W004292S1 1-Undecanol-d4 / Unkown
HY-RS17512 Trap1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23969 Trap1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trap1 NCBI NCBI:10131