2. Gene
  3. Yme1l1 - YME1-like 1 (S. cerevisiae) Gene

Yme1l1 - YME1-like 1 (S. cerevisiae) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ftsh; FtsH1

Gene ID: 27377 | Gene type: protein coding

About Yme1l1

Summary

Enables ATP-dependent peptidase activity. Involved in mitochondrial protein processing. Located in mitochondrion. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in optic atrophy 11. Orthologous to human YME1L1 (YME1 like 1 ATPase). [provided by Alliance of Genome Resources, Apr 2022]

Yme1l1 Products(1)

mRNA Protein Name
NM_013771.5 NP_038799.1 ATP-dependent zinc metalloprotease YME1L1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables ATP-dependent peptidase activity IDA
IDA: Inferred from direct assay
24703695 MGI
enables ATP-dependent peptidase activity IMP
IMP: Inferred from mutant phenotype
27495975 MGI
Biological Process GO Annotation Evidence Reference Source
involved in mitochondrial protein processing IMP
IMP: Inferred from mutant phenotype
27495975 MGI
involved in neuronal stem cell population maintenance IDA
IDA: Inferred from direct assay
35172139 MGI
involved in positive regulation of mitochondrial fusion IDA
IDA: Inferred from direct assay
33237841 MGI
involved in regulation of stem cell division IDA
IDA: Inferred from direct assay
35172139 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-dependent zinc metalloprotease YME1L1

ATP-dependent metalloprotease FtsH1

YME1-like protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15929 YME1L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21219 Yme1l1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27735 Yme1l1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Yme1l1 NCBI NCBI:10730