2. Gene
  3. Epb41 - erythrocyte membrane protein band 4.1 Gene

Epb41 - erythrocyte membrane protein band 4.1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 4.1R; Elp1; Elp-1; Epb4.1; mKIAA4056; D4Ertd442e

Gene ID: 269587 | Gene type: protein coding

About Epb41

Summary

Predicted to enable several functions, including 1-phosphatidylinositol binding activity; cytoskeletal protein binding activity; and protein C-terminus binding activity. Involved in regulation of calcium ion transport and regulation of intestinal absorption. Acts upstream of or within positive regulation of protein binding activity. Located in basolateral plasma membrane and cortical Cytoskeleton. Is expressed in several structures, including alimentary system; brain; connective tissue; eye; and genitourinary system. Used to study hereditary elliptocytosis. Orthologous to human EPB41 (erythrocyte membrane protein band 4.1). [provided by Alliance of Genome Resources, Apr 2022]

Epb41 Products(3)

mRNA Protein Name
NM_001128606.1 NP_001122078.1 protein 4.1 isoform 2
NM_001128607.2 NP_001122079.1 protein 4.1 isoform 3
NM_183428.3 NP_906273.3 protein 4.1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18987665 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of protein binding IGI
IGI: Inferred from genetic interaction
20585040 MGI
involved in regulation of calcium ion transport IMP
IMP: Inferred from mutant phenotype
23460639 MGI
involved in regulation of intestinal absorption IMP
IMP: Inferred from mutant phenotype
23460639 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
23460639 MGI
located in cortical cytoskeleton IDA
IDA: Inferred from direct assay
18723693 MGI
located in membrane IDA
IDA: Inferred from direct assay
18723693 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein 4.1

P4.1

Protein 4.1R

band 4.1

erythrocyte protein band 4.1

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04410 EPB41 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04411 EPB41L1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04412 EPB41L2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04413 EPB41L3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04414 EPB41L4A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04415 EPB41L4B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04416 EPB41L5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22488 Epb41 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epb41 NCBI NCBI:2035