2. Gene
  3. Ffar1 - free fatty acid receptor 1 Gene

Ffar1 - free fatty acid receptor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Gpr40

Gene ID: 266607 | Gene type: protein coding

About Ffar1

Summary

Enables fatty acid binding activity. Involved in G protein-coupled receptor signaling pathway; positive regulation of calcium ion transport into cytosol; and positive regulation of Insulin secretion. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FFAR1 (Free Fatty Acid Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ffar1 Products(1)

mRNA Protein Name
NM_153304.2 NP_695216.1 free fatty acid receptor 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables fatty acid binding IDA
IDA: Inferred from direct assay
12496284 RGD
Biological Process GO Annotation Evidence Reference Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12496284 RGD
involved in positive regulation of calcium ion transport into cytosol IMP
IMP: Inferred from mutant phenotype
15914509 RGD
involved in positive regulation of insulin secretion IMP
IMP: Inferred from mutant phenotype
16081037 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

free fatty acid receptor 1

G-protein coupled receptor 40

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101906 DC260126 99.74% Unkown
HY-W009081 Tricosanoic acid Agonist 99.96% Unkown
HY-W040127 Peonidin 3-O-glucoside chloride 98.02% Unkown
HY-147351 GPR40 agonist 6 Agonist 98.81% Unkown
HY-111763 GPR40/FFAR1 modulator 1 Agonist 98.28% Unkown
HY-148418 TUG-499 Agonist 99.78% Unkown
HY-148235 TP-051 Agonist / Unkown
HY-148247 BI-2081 Agonist / Unkown
HY-164870 FFAR1/FFAR4 agonist-1 Agonist / Unkown
HY-RS04874 FFAR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16972 Ffar1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23415 Ffar1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ffar1 NCBI NCBI:2864