2. Gene
  3. Map3k11 - mitogen-activated protein kinase kinase kinase 11 Gene

Map3k11 - mitogen-activated protein kinase kinase kinase 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Mlk3; PTK1; SPRK; 2610017K16Rik

Gene ID: 26403 | Gene type: protein coding

About Map3k11

Summary

Predicted to enable several functions, including ATP binding activity; JUN kinase kinase kinase activity; and enzyme binding activity. Predicted to be involved in several processes, including JNK cascade; positive regulation of MAPK cascade; and positive regulation of neuron apoptotic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in microtubule. Predicted to be active in centrosome. Is expressed in blood vessel and brain. Orthologous to human MAP3K11 (mitogen-activated protein kinase kinase kinase 11). [provided by Alliance of Genome Resources, Apr 2022]

Map3k11 Products(1)

mRNA Protein Name
NM_022012.3 NP_071295.2 mitogen-activated protein kinase kinase kinase 11
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15767678 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitogen-activated protein kinase kinase kinase 11

mixed lineage kinase 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08048 MAP3K11 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20638 Map3k11 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27147 Map3k11 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map3k11 NCBI NCBI:4296