2. Gene
  3. Hck - HCK proto-oncogene, Src family tyrosine kinase Gene

Hck - HCK proto-oncogene, Src family tyrosine kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hctk; p56Hck; p59Hck

Gene ID: 25734 | Gene type: protein coding

About Hck

Summary

The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types.The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms in human and mouse. Based on strong sequence conservation amongst these species, this may also be true for rat. [provided by RefSeq, Jul 2008]

Hck Products(1)

mRNA Protein Name
NM_013185.3 NP_037317.2 tyrosine-protein kinase HCK
Protein Preferred Names Protein Names

tyrosine-protein kinase HCK

hematopoietic cell kinase

hemopoietic cell kinase

hemopoietic cell tyrosine kinase

p56-HCK

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-157442 GLPG3312 Inhibitor 98.57% Phase 1
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-175451 MRT-10350 Degrader / Unkown
HY-176194 Antifibrotic agent 1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hck NCBI NCBI:3055