2. Gene
  3. Fkbp1a - FKBP prolyl isomerase 1A Gene

Fkbp1a - FKBP prolyl isomerase 1A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Fkbp2; FKBP12

Gene ID: 25639 | Gene type: protein coding

About Fkbp1a

Summary

Enables several functions, including FK506 binding activity; HSP70 protein binding activity; and type I transforming growth factor beta receptor binding activity. Involved in response to iron ion. Located in axon terminus and intracellular membrane-bounded organelle. Biomarker of Parkinsonism. Orthologous to several human genes including FKBP1A (FKBP prolyl isomerase 1A). [provided by Alliance of Genome Resources, Apr 2022]

Fkbp1a Products(1)

mRNA Protein Name
NM_013102.3 NP_037234.2 peptidyl-prolyl cis-trans isomerase FKBP1A
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables FK506 binding IDA
IDA: Inferred from direct assay
9013543 RGD
enables Hsp70 protein binding IPI
IPI: Inferred from physical interaction
17877381 RGD
enables enzyme binding IPI
IPI: Inferred from physical interaction
17877381 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
17877381 RGD
enables transforming growth factor beta receptor binding IDA
IDA: Inferred from direct assay
7518616 RGD
enables type I transforming growth factor beta receptor binding IDA
IDA: Inferred from direct assay
7518616 RGD
Biological Process GO Annotation Evidence Reference Source
involved in response to iron ion IEP
IEP: Inferred from expression pattern
17546681 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon terminus IDA
IDA: Inferred from direct assay
12494287 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase FKBP1A

12 kDa FK506-binding protein

12 kDa FKBP

FK506 binding protein 1a

FK506 binding protein 2 (13 kDa)

FK506-binding protein 1 (12kD)

FK506-binding protein 1A

FKBP-12

FKBP-1A

PPIase FKBP1A

immunophilin FKBP12

rotamase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04960 FKBP1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18309 Fkbp1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24787 Fkbp1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fkbp1a NCBI NCBI:2280
Mus musculus Fkbp1a NCBI NCBI:14225