2. Gene
  3. Id2 - inhibitor of DNA binding 2 Gene

Id2 - inhibitor of DNA binding 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ac2-300

Gene ID: 25587 | Gene type: protein coding

About Id2

Summary

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; transcription regulator inhibitor activity; and transmembrane transporter binding activity. Involved in several processes, including cellular response to follicle-stimulating hormone stimulus; negative regulation of macromolecule metabolic process; and positive regulation of cell population proliferation. Located in chromatin; cytosol; and nucleus. Orthologous to human ID2 (inhibitor of DNA binding 2). [provided by Alliance of Genome Resources, Apr 2022]

Id2 Products(1)

mRNA Protein Name
NM_013060.4 NP_037192.1 DNA-binding protein inhibitor ID-2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15831523 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to follicle-stimulating hormone stimulus IEP
IEP: Inferred from expression pattern
14761970 RGD
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
11706002 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11706002 RGD
involved in neuron differentiation IEP
IEP: Inferred from expression pattern
7908517 RGD
involved in positive regulation of cell cycle IDA
IDA: Inferred from direct assay
11706002 RGD
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
11706002 RGD
Cellular Component GO Annotation Evidence Reference Source
located in chromatin IDA
IDA: Inferred from direct assay
16776654 RGD
located in cytoplasm IDA
IDA: Inferred from direct assay
11301021 RGD
located in nucleus IDA
IDA: Inferred from direct assay
11301021 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-binding protein inhibitor ID-2

inhibitor of DNA binding 2, HLH protein

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

inhibitor of differentiation 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N4058 Helichrysetin Inducer 99.92% Unkown
HY-144707 AK-778-XXMU Inducer 98.82% Unkown
HY-119966 CCT036477 Inhibitor 99.42% Unkown
HY-155705 BMP agonist 1 / Unkown
HY-RS06523 ID2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17244 Id2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23698 Id2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Id2 NCBI NCBI:3398