2. Gene
  3. Ubtf - upstream binding transcription factor Gene

Ubtf - upstream binding transcription factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Tcfubf

Gene ID: 25574 | Gene type: protein coding

About Ubtf

Summary

Predicted to enable several functions, including RNA polymerase I general transcription initiation factor activity; RNA polymerase I transcription regulatory region sequence-specific DNA binding activity; and scaffold protein binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase I and transcription initiation from RNA polymerase I promoter. Predicted to act upstream of or within cellular response to leukemia inhibitory factor; rDNA heterochromatin assembly; and transcription elongation from RNA polymerase I promoter. Located in fibrillar center. Orthologous to human UBTF (upstream binding transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Ubtf Products(2)

mRNA Protein Name
NM_001105723.3 NP_001099193.2 nucleolar transcription factor 1 isoform 1
NM_001127690.2 NP_001121162.1 nucleolar transcription factor 1 isoform 2
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17251981 RGD
Cellular Component GO Annotation Evidence Reference Source
located in fibrillar center IDA
IDA: Inferred from direct assay
17587596 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleolar transcription factor 1

UBF-1

transcription factor UBF

upstream binding transcription factor, RNA polymerase I

upstream-binding factor 1

Ubtf Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Ubtf P25977 Runx2 Rattus norvegicus Q9Z2J9
Anti Bait CoIP
17251981
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15393 UBTF Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19167 Ubtf Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25656 Ubtf Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ubtf NCBI NCBI:7343