Ptprs - protein tyrosine phosphatase, receptor type, S Gene

Rattus norvegicus

Also known as Ptprd; Rptpd; Larptp2; Ptpsigma; Ptpsigma.

Gene ID: 25529 | Gene type: protein coding

About Ptprs

Summary

Enables protein tyrosine Phosphatase activity. Involved in regulation of postsynaptic density assembly; regulation of presynapse assembly; and synaptic membrane adhesion. Is integral component of postsynaptic density membrane and integral component of synaptic vesicle membrane. Is active in glutamatergic synapse. Is integral component of presynaptic membrane. Orthologous to human PTPRS (protein tyrosine Phosphatase receptor type S). [provided by Alliance of Genome Resources, Apr 2022]

Ptprs Products(1)

mRNA	Protein	Name
NM_019140.3	NP_062013.2	receptor-type tyrosine-protein phosphatase S precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein tyrosine phosphatase activity	IDA IDA: Inferred from direct assay	8068021	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in presynapse assembly	EXP EXP: Inferred from Experiment	21262467	RGD
involved in presynapse assembly	IDA IDA: Inferred from direct assay	21262467	RGD
involved in presynapse assembly	IMP IMP: Inferred from mutant phenotype	21262467	RGD
involved in regulation of postsynaptic density assembly	EXP EXP: Inferred from Experiment	21262467	RGD
involved in regulation of postsynaptic density assembly	IDA IDA: Inferred from direct assay	21262467	RGD
involved in regulation of postsynaptic density assembly	IMP IMP: Inferred from mutant phenotype	21262467	RGD
involved in synaptic membrane adhesion	IDA IDA: Inferred from direct assay	20139422	RGD
involved in synaptic membrane adhesion	IMP IMP: Inferred from mutant phenotype	20139422	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	EXP EXP: Inferred from Experiment	21262467	RGD
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	21262467	RGD
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	21262467	RGD
located in postsynaptic density membrane	IDA IDA: Inferred from direct assay	22519304	RGD
is active in presynaptic membrane	IDA IDA: Inferred from direct assay	21262467	RGD
located in synaptic vesicle membrane	IDA IDA: Inferred from direct assay	22519304	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

receptor-type tyrosine-protein phosphatase S

LAR-PTP2	R-PTP-S
R-PTP-sigma	leukocyte common antigen-related protein-tyrosine phosphatase 2
leukocyte common antigen-related proten-tyrosine phosphatase 2	protein tyrosine phosphatase, receptor type, D
receptor-type tyrosine-protein phosphatase sig

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11449	PTPRS Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21709	Ptprs Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS28227	Ptprs Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ptprs	NCBI	NCBI:5802

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