2. Gene
  3. Dlx5 - distal-less homeobox 5 Gene

Dlx5 - distal-less homeobox 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RDLX

Gene ID: 25431 | Gene type: protein coding

About Dlx5

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of osteoblast differentiation. Predicted to be located in chromatin; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in split hand-foot malformation 1 and split hand-foot malformation 1 with sensorineural hearing loss. Orthologous to human DLX5 (distal-less homeobox 5). [provided by Alliance of Genome Resources, Apr 2022]

Dlx5 Products(1)

mRNA Protein Name
NM_012943.1 NP_037075.1 homeobox protein DLX-5
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to zinc ion starvation IEP
IEP: Inferred from expression pattern
21893222 RGD
involved in positive regulation of osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
12815054 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein DLX-5

DLX-3

homeobox protein DLX-3

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03816 DLX5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19892 Dlx5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24208 Dlx2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26392 Dlx5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dlx5 NCBI NCBI:1749