2. Gene
  3. Fth1 - ferritin heavy chain 1 Gene

Fth1 - ferritin heavy chain 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Fth

Gene ID: 25319 | Gene type: protein coding

About Fth1

Summary

Predicted to enable ferric iron binding activity and ferrous iron binding activity. Involved in negative regulation of fibroblast proliferation and negative regulation of necrotic cell death. Predicted to be located in autolysosome. Predicted to be active in cytoplasm. Biomarker of congestive heart failure and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in hemochromatosis type 5. Orthologous to human FTH1 (ferritin heavy chain 1). [provided by Alliance of Genome Resources, Apr 2022]

Fth1 Products(1)

mRNA Protein Name
NM_012848.2 NP_036980.1 ferritin heavy chain
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19244528 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of fibroblast proliferation IDA
IDA: Inferred from direct assay
9924025 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ferritin heavy chain

Ferritin subunit H

ferritin H subunit

ferritin, heavy polypeptide 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148409 MMRi62 99.58% Unkown
HY-RS05133 FTH1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-168894 CT-1 Inducer / Unkown
HY-RS16862 Fth1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23303 Fth1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fth1 NCBI NCBI:2495