2. Gene
  3. EPHX4 - epoxide hydrolase 4 Gene

EPHX4 - epoxide hydrolase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as EH4; ABHD7; EPHXRP

Gene ID: 253152 | Gene type: protein coding

About EPHX4

Cytogenetic location: 1p22.1 Genomic coordinates (GRCh38): 1:92,029,985-92,063,538 (from NCBI)

This gene has 2 transcripts (splice variants), 226 orthologues and 12 paralogues. Biased expression in brain (RPKM 5.0), thyroid (RPKM 1.1) and 9 other tissues.

Summary

Predicted to enable hydrolase activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

EPHX4 Products(1)

mRNA Protein Name
NM_173567.5 NP_775838.3 epoxide hydrolase 4
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EPHX4 Protein Structure

Abhydrolase_6

Abhydrolase_6: Alpha/beta hydrolase family (97 - 348)

  • 0
  • 100
  • 200
  • 300
  • 362 a.a.
Protein Preferred Names Protein Names

epoxide hydrolase 4

abhydrolase domain containing 7

EPHX4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
EPHX4 Q8IUS5 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Intra
EPHX4 Q8IUS5 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
Intra
EPHX4 Q8IUS5 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04440 EPHX4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus EPHX4 VGNC VGNC:28544
Mus musculus EPHX4 MGD MGI:2686228
Macaca mulatta EPHX4 VGNC VGNC:81394
Canis familiaris EPHX4 VGNC VGNC:40417
Rattus norvegicus EPHX4 RGD RGD:1308891
Felis catus EPHX4 VGNC VGNC:80197