2. Gene
  3. Lgi1 - leucine-rich, glioma inactivated 1 Gene

Lgi1 - leucine-rich, glioma inactivated 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 252892 | Gene type: protein coding

About Lgi1

Summary

Predicted to enable signaling receptor binding activity. Involved in positive regulation of synaptic transmission. Located in extracellular space and synapse. Used to study epilepsy and epilepsy with generalized tonic-clonic seizures. Human ortholog(s) of this gene implicated in familial temporal lobe epilepsy 1. Orthologous to human LGI1 (leucine rich glioma inactivated 1). [provided by Alliance of Genome Resources, Apr 2022]

Lgi1 Products(1)

mRNA Protein Name
NM_145769.4 NP_665712.1 leucine-rich glioma-inactivated protein 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16504945 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of synaptic transmission IDA
IDA: Inferred from direct assay
16990550 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon initial segment IDA
IDA: Inferred from direct assay
30598502 RGD
located in dendrite IDA
IDA: Inferred from direct assay
30598502 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
16990550 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich glioma-inactivated protein 1

leucine-rich glioma-inactivated protein 1-like

leucine-rich repeat LGI family, member 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07613 LGI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22218 Lgi1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28740 Lgi1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lgi1 NCBI NCBI:9211