2. Gene
  3. Usp7 - ubiquitin specific peptidase 7 Gene

Usp7 - ubiquitin specific peptidase 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hausp; 2210010O09Rik

Gene ID: 252870 | Gene type: protein coding

About Usp7

Summary

Enables cysteine-type endopeptidase activity and thiol-dependent Deubiquitinase. Involved in histone H2B conserved C-terminal lysine deubiquitination; regulation of circadian rhythm; and regulation of protein stability. Located in XY body; cytoplasm; and nucleus. Is expressed in embryo and trophectoderm. Orthologous to human USP7 (ubiquitin specific peptidase 7). [provided by Alliance of Genome Resources, Apr 2022]

Usp7 Products(1)

mRNA Protein Name
NM_001003918.2 NP_001003918.2 ubiquitin carboxyl-terminal hydrolase 7
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables cysteine-type deubiquitinase activity IDA
IDA: Inferred from direct assay
21268065 MGI
enables cysteine-type deubiquitinase activity IMP
IMP: Inferred from mutant phenotype
27863226 MGI
enables cysteine-type endopeptidase activity IMP
IMP: Inferred from mutant phenotype
21268065 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18716620 MGI
Biological Process GO Annotation Evidence Reference Source
involved in protein deubiquitination IDA
IDA: Inferred from direct assay
21268065 MGI
involved in regulation of circadian rhythm IMP
IMP: Inferred from mutant phenotype
27123980 MGI
involved in regulation of protein stability IMP
IMP: Inferred from mutant phenotype
27123980 MGI
involved in transcription elongation-coupled chromatin remodeling IMP
IMP: Inferred from mutant phenotype
27863226 MGI
Cellular Component GO Annotation Evidence Reference Source
located in XY body IDA
IDA: Inferred from direct assay
25634095 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12093161 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12093161 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 7

deubiquitinating enzyme 7

herpesvirus-associated ubiquitin-specific protease

mHAUSP

ubiquitin specific protease 7

ubiquitin thioesterase 7

ubiquitin thiolesterase 7

ubiquitin-specific-processing protease 7

Related Agents

Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101666 HBX 41108 Inhibitor 98.91% Unkown
HY-136910 USP7-797 Inhibitor 99.09% Unkown
HY-148369 U7D-1 Inhibitor 99.68% Unkown
HY-158039 YCH2823 Inhibitor 99.87% Unkown
HY-159175 XM-U-14 Degrader / Unkown
HY-159964 USP7-IN-16 Inhibitor / Unkown
HY-153942 USP7-IN-12 Inhibitor / Unkown
HY-168121 USP7-IN-15 Inhibitor / Unkown
HY-162794 YCH3124 Inhibitor / Unkown
HY-164544 USP7-055 Inhibitor / Unkown
HY-124739 HBX 28258 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp7 NCBI NCBI:7874