2. Gene
  3. Vav1 - vav guanine nucleotide exchange factor 1 Gene

Vav1 - vav guanine nucleotide exchange factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Vav

Gene ID: 25156 | Gene type: protein coding

About Vav1

Summary

Predicted to enable guanyl-nucleotide exchange factor activity; phosphorylation-dependent protein binding activity; and phosphotyrosine residue binding activity. Involved in immune response-regulating cell surface receptor signaling pathway. Predicted to be located in cell-cell junction. Biomarker of endometriosis; hepatocellular carcinoma; lymphopenia; and type 1 diabetes mellitus. Orthologous to human VAV1 (vav guanine nucleotide exchange factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Vav1 Products(1)

mRNA Protein Name
NM_012759.2 NP_036891.2 proto-oncogene vav
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in immune response-regulating cell surface receptor signaling pathway IEP
IEP: Inferred from expression pattern
1531699 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proto-oncogene vav

p95

vav 1 guanine nucleotide exchange factor

vav 1 oncogene

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-168625 VAV1 degrader-3 99.26% Unkown
HY-RS15612 VAV1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-131598C 6-Thio-GTP tetrasodium Inhibitor / Unkown
HY-168624 VAV1 degrader-2 / Unkown
HY-RS20834 Vav1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27348 Vav1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vav1 NCBI NCBI:7409