2. Gene
  3. Gadd45a - growth arrest and DNA-damage-inducible, alpha Gene

Gadd45a - growth arrest and DNA-damage-inducible, alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ddit1; Gadd45

Gene ID: 25112 | Gene type: protein coding

About Gadd45a

Summary

Predicted to enable several functions, including promoter-specific chromatin binding activity; protein N-terminus binding activity; and protein dimerization activity. Involved in G2/M transition of mitotic cell cycle. Predicted to be located in nuclear speck. Predicted to be active in cytoplasm and nucleus. Orthologous to human GADD45A (growth arrest and DNA damage inducible alpha). [provided by Alliance of Genome Resources, Apr 2022]

Gadd45a Products(1)

mRNA Protein Name
NM_024127.2 NP_077041.2 growth arrest and DNA damage-inducible protein GADD45 alpha
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in G2/M transition of mitotic cell cycle IEP
IEP: Inferred from expression pattern
11964479 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth arrest and DNA damage-inducible protein GADD45 alpha

DDIT-1

DNA damage-inducible transcript 1 protein

DNA-damage-inducible transcript 1

growth arrest and DNA-damage-inducible 45 alpha

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10587 BIX-01294 98.44% Unkown
HY-108239 BIX-01294 trihydrochloride / Unkown
HY-RS05229 GADD45A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17861 Gadd45a Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24330 Gadd45a Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gadd45a NCBI NCBI:1647