2. Gene
  3. Apoa4 - apolipoprotein A4 Gene

Apoa4 - apolipoprotein A4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as apoAIV; Apo-AIV; ApoA-IV

Gene ID: 25080 | Gene type: protein coding

About Apoa4

Summary

Predicted to enable several functions, including cation binding activity; Cholesterol binding activity; and Cholesterol transfer activity. Involved in peripheral nervous system axon regeneration and response to triglyceride. Part of chylomicron. Is active in synapse. Biomarker of major depressive disorder. Human ortholog(s) of this gene implicated in Alzheimer's disease; colitis; myocardial infarction; and ulcerative colitis. Orthologous to human APOA4 (Apolipoprotein A4). [provided by Alliance of Genome Resources, Apr 2022]

Apoa4 Products(1)

mRNA Protein Name
NM_012737.2 NP_036869.2 apolipoprotein A-IV precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in peripheral nervous system axon regeneration IEP
IEP: Inferred from expression pattern
2120218 RGD
involved in response to triglyceride IEP
IEP: Inferred from expression pattern
21472381 RGD
Cellular Component GO Annotation Evidence Reference Source
part of chylomicron IDA
IDA: Inferred from direct assay
6591177 RGD
is active in synapse EXP
EXP: Inferred from Experiment
15169875 RGD
is active in synapse IDA
IDA: Inferred from direct assay
15169875 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

apolipoprotein A-IV

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00831 APOA4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19408 Apoa4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25900 Apoa4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Apoa4 NCBI NCBI:337
Mus musculus Apoa4 NCBI NCBI:11808