2. Gene
  3. Calcrl - calcitonin receptor like receptor Gene

Calcrl - calcitonin receptor like receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CLR; Crlr; RNCLR; RATCRLR

Gene ID: 25029 | Gene type: protein coding

About Calcrl

Summary

Predicted to enable Adrenomedullin binding activity; Adrenomedullin receptor activity; and Calcitonin gene-related peptide receptor activity. Involved in negative regulation of inflammatory response and negative regulation of smooth muscle contraction. Predicted to be located in endoplasmic reticulum; endosome; and lysosome. Predicted to be part of CGRP Receptor complex and Adrenomedullin receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human CALCRL (Calcitonin receptor like receptor). [provided by Alliance of Genome Resources, Apr 2022]

Calcrl Products(1)

mRNA Protein Name
NM_012717.3 NP_036849.2 calcitonin gene-related peptide type 1 receptor precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of smooth muscle contraction IMP
IMP: Inferred from mutant phenotype
17363466 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in neuronal dense core vesicle IDA
IDA: Inferred from direct assay
17614212 RGD
is active in synaptic vesicle IDA
IDA: Inferred from direct assay
17614212 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcitonin gene-related peptide type 1 receptor

CGRP type 1 receptor

calcitonin receptor-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-176305S Neurofilament, U-15N / Unkown
HY-RS01835 CALCRL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20140 Calcrl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26644 Calcrl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Calcrl NCBI NCBI:10203