1. Gene
  2. Sts - steroid sulfatase Gene

Sts - steroid sulfatase Gene

Rattus norvegicus
Gene ID: 24800 | Gene type: protein coding

About Sts

Summary

Enables steryl-sulfatase activity. Involved in several processes, including response to estrogen; response to pH; and response to peptide hormone. Located in endoplasmic reticulum membrane and nuclear envelope. Is integral component of membrane. Biomarker of cryptorchidism and hypertension. Human ortholog(s) of this gene implicated in X-linked ichthyosis. Orthologous to human STS (Steroid Sulfatase). [provided by Alliance of Genome Resources, Apr 2022]

Sts Products(1)

mRNA Protein Name
NM_012661.2 NP_036793.2 steryl-sulfatase precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables steryl-sulfatase activity IDA
IDA: Inferred from direct assay
8662223 RGD
Biological Process GO Annotation Evidence Reference Source
involved in learning or memory IMP
IMP: Inferred from mutant phenotype
10821934 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
17268815 RGD
involved in response to estrogen IDA
IDA: Inferred from direct assay
2965775 RGD
involved in response to organic cyclic compound IDA
IDA: Inferred from direct assay
11282279 RGD
involved in response to pH IDA
IDA: Inferred from direct assay
6586719 RGD
involved in response to peptide hormone IDA
IDA: Inferred from direct assay
2779233 RGD
involved in skin development IEP
IEP: Inferred from expression pattern
9182813 RGD
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
2703703 RGD
located in nuclear envelope IDA
IDA: Inferred from direct assay
2703703 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

steryl-sulfatase

ASC

arylsulfatase C

steroid sulfatase (microsomal), isozyme S

steryl-sulfate sulfohydrolase

Orthologs Information

Species Symbol Source ID
Homo sapiens Sts NCBI NCBI:412