2. Gene
  3. Mx1 - MX dynamin like GTPase 1 Gene

Mx1 - MX dynamin like GTPase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as IFI78

Gene ID: 24575 | Gene type: protein coding

About Mx1

Summary

Predicted to enable GTPase activity; identical protein binding activity; and microtubule binding activity. Involved in response to virus. Located in nucleus. Human ortholog(s) of this gene implicated in alopecia areata; avian influenza; liver disease; and prostate Cancer. Orthologous to human MX1 (MX Dynamin like GTPase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mx1 Products(6)

mRNA Protein Name
NM_001271058.1 NP_001257987.1 interferon-induced GTP-binding protein Mx1
NM_001271059.1 NP_001257988.1 interferon-induced GTP-binding protein Mx1
NM_001271060.1 NP_001257989.1 interferon-induced GTP-binding protein Mx1
NM_001271061.1 NP_001257990.1 interferon-induced GTP-binding protein Mx1
NM_001271062.1 NP_001257991.1 interferon-induced GTP-binding protein Mx1
NM_173096.3 NP_775119.2 interferon-induced GTP-binding protein Mx1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in response to virus IDA
IDA: Inferred from direct assay
2173790 RGD
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
2173790 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interferon-induced GTP-binding protein Mx1

Myxovirus (influenza) resistance, homolog of murine Mx (also interferon-inducible protein IFI78)

myxoma resistance protein 1

myxovirus (influenza virus) resistance 1

myxovirus resistance protein 1

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-106031 F-14512 97.48% Phase 2
HY-12098 Verubulin hydrochloride Inhibitor 98.71% Phase 2
Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0167 Gynostemma Extract 99.92% Unkown
HY-123805 KIN1400 98.1% Unkown
HY-155113 PROTAC Hsp90α degrader 1 Degrader / Unkown
HY-14687 (rac)-Talazoparib Inhibitor / Unkown
HY-RS08859 MX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-121372 Lactandrate / Unkown
HY-N14478 Saframycin Mx1 Inhibitor / Unkown
HY-RS18454 Mx1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24935 Mx1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mx1 NCBI NCBI:4599